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Antibiotic resistance
CFG 01/02 rev. 1

The risk to human health and safety from the use of antibiotics in animal production.

Foodaware draws attention to the problem of antibiotic resistance and the consequent reduction in the effectiveness of antibiotics used to treat infections in humans, with increasingly fatal consequences. Antibiotics have a vital role to play in human and animal medicine. However, antibiotic resistance in human medicine has increased dramatically over the past 25 years and Foodaware is aware that no new antibiotics are likely to become available in the near future.

Foodaware recognises that this is a global problem. The risk to human health from antibiotic resistant bacteria is so great that any way of reducing it must be examined and acted upon.

Foodaware acknowledges that the increase in antibiotic resistant bacteria occurring in human medicine may result from excessive and unnecessary use of antibiotics in treating infections in humans.

Foodaware notes that there is widespread concern about the transfer of antibiotic resistant bacteria from animals to humans. Humans can acquire resistant bacteria from animals, directly via food or through contact with the animal or animal foodstuff or from living near to farm animals.

Foodaware is aware that antibiotics are used widely in farming - as therapeutic medicines, as routine prophylaxis and as growth promoters - and that their usage in animals may be excessive and unnecessary.

Foodaware notes that resistant strains of four bacteria - Salmonella, Campylobacter, Enterococci and E.coli, which cause disease in humans, have been transmitted from animals to humans, and shown to have adverse consequences for human health.

Foodaware is aware that over the past 25 years multiple resistance to antibiotics has been increasing for the most common salmonella infections in humans. There has been a similar upward trend in the same salmonellas in food animals. One strain of Salmonella typhimurium is now resistant to five of the most commonly used antibiotics.

Foodaware is aware that antibiotic-resistant enterococcus can transmit its resistance to other bacteria and it is suspected that antibiotic resistant bacteria may be selected in the animal, contaminate the foodstuff and transfer resistance to other bacteria in the human gut.

Foodaware is extremely concerned about bacterial cross-resistance to antibiotics within the same group. This is happening within the following groups: the glycopeptides, fluoroquinolones, macrolides and, most recently, the streptogramins. Antibiotics used in animal medicine are not sufficiently dissimilar to those used in human medicine.

Foodaware is very aware of the difficulty of obtaining comprehensive data on the use of all antibiotics on farms in the UK and many other EU Member States. Data are needed on the amount used in animals for each type of use (growth promotion, prophylactic and therapeutic), which antibiotics are used and which antibiotics are also used in human medicine, in order to assess the real impact of the use of antibiotics in livestock production.

Foodaware considers that the whole issue of antibiotic resistance needs to be examined at EU level and welcomes the Commission proposal to do so. Mechanisms in the EU for monitoring and controlling the spread of antibiotic resistance are inadequate. There is a lack of co-ordination, transparency and independence in the EU Scientific Committees on antibiotics and those Committees lack experts on antibiotics.

Foodaware is aware of concerns about antibiotic resistance in Sweden, Finland and Denmark, where there is stricter legislation on antibiotic usage in animal feedstuffs.

Foodaware considers that antibiotic resistance is a prime example of an issue to which the precautionary principle should have been applied at an early stage, and an issue which demonstrates why it is so important to apply the precautionary principle.

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RECOMMENDATIONS

Foodaware calls for:
  • A rigorous precautionary approach to the use of antibiotics in both humans and animals, with the aim of achieving:-
    • a total ban on the use of antibiotics as growth promoters in animal feedstuffs within the European Union.
    • a ban on the prophylactic use of antibiotics except where disease has been identified in an animal within a group of animals.
    • a ban within the EU on the prophylactic use of antibiotics in animal medicine which have actual or potential cross-resistance to those used in human medicine.
  • All antibiotic usage in animals to be subject to veterinary prescription.
  • A specific EU policy to reduce the therapeutic and prophylactic use of antibiotics in animals over the short to medium term.
  • A coherent EU-wide strategy to improve hygiene on farms, with firm monitoring. This could cut down substantially on the need for prophylactic and therapeutic antibiotic treatment.
  • Within CODEX and WHO, priority to be given to measures to reduce antibiotic resistance because it is a global issue.
  • EU guidelines to be drawn up governing best practice in both animal and human medicine to ensure that all antibiotics are prescribed rationally.
  • The EU to undertake a comprehensive analysis of the levels of antibiotic use in Member States and to examine the reasons for any differences between Member States. This could be done under the Scientific Co-operation Programme (SCOOP). A specific EU Scientific Committee should be given responsibility to examine the risk to human health from the use of antibiotics in animals and animal production. A multidisciplinary approach to the issue must be taken by including human health and food scientists.
  • More transparency in the decision-making process of EU scientific and regulatory committees working on antibiotics.
  • A ban on antibiotic marker genes in genetically modified crops.
  • EU Member States which currently have more stringent controls on antibiotic usage in animals to be able to retain them in the interest of human health protection.
May 2002

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